Botox

Black Box Warning

Generic: onabotulinumtoxinA

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Information reviewed July 24, 2026

Rank #133 in US TV Ads
Class: Neurotoxin

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What is it for?

An injectable treatment for chronic migraine in adults who have headaches on 15 or more days a month, given as a series of small injections every 12 weeks.

Primary Condition

Chronic migraine

How it works

A purified neurotoxin that blocks the release of chemicals involved in pain signaling, preventing migraine headaches before they start.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Neck pain
  • Headache
  • Drooping eyelid
  • Muscle weakness
  • Possible spread of toxin effects

Botox FAQs

What is Botox used for?

Botox (onabotulinumtoxinA) is a prescription medication used to treat Chronic migraine. An injectable treatment for chronic migraine in adults who have headaches on 15 or more days a month, given as a series of small injections every 12 weeks.

How does Botox work?

A purified neurotoxin that blocks the release of chemicals involved in pain signaling, preventing migraine headaches before they start.

What are the common side effects of Botox?

Commonly reported side effects of Botox include Neck pain, Headache, Drooping eyelid, Muscle weakness, and Possible spread of toxin effects. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Botox have any serious warnings?

Yes. Botox carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Botox?

The active ingredient in Botox is onabotulinumtoxinA, which belongs to a class of medicines known as Neurotoxin.

Who makes Botox?

Botox is manufactured by AbbVie. It was first approved in 2010.

How can I save money on Botox?

You may be able to lower the cost of Botox by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Botox

Other Neurology medications

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Quick Facts

Manufacturer

AbbVie

Year Approved

2010

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