Calquence

Moderate Warnings

Generic: acalabrutinib

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Information reviewed July 24, 2026

Rank #126 in US TV Ads
Class: BTK Inhibitor

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What is it for?

An oral targeted treatment for chronic lymphocytic leukemia (CLL) and mantle cell lymphoma.

Primary Condition

Chronic lymphocytic leukemia and mantle cell lymphoma

How it works

A BTK inhibitor that blocks a signaling protein these cancer cells need to survive and multiply.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Headache
  • Diarrhea
  • Bruising and bleeding
  • Infections
  • Irregular heartbeat

Calquence FAQs

What is Calquence used for?

Calquence (acalabrutinib) is a prescription medication used to treat Chronic lymphocytic leukemia and mantle cell lymphoma. An oral targeted treatment for chronic lymphocytic leukemia (CLL) and mantle cell lymphoma.

How does Calquence work?

A BTK inhibitor that blocks a signaling protein these cancer cells need to survive and multiply.

What are the common side effects of Calquence?

Commonly reported side effects of Calquence include Headache, Diarrhea, Bruising and bleeding, Infections, and Irregular heartbeat. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Calquence have any serious warnings?

Calquence has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Calquence.

What is the generic name for Calquence?

The active ingredient in Calquence is acalabrutinib, which belongs to a class of medicines known as BTK Inhibitor.

Who makes Calquence?

Calquence is manufactured by AstraZeneca. It was first approved in 2017.

How can I save money on Calquence?

You may be able to lower the cost of Calquence by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Calquence

Other Oncology medications

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Quick Facts

Manufacturer

AstraZeneca

Year Approved

2017

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