Descovy
Generic: emtricitabine/tenofovir alafenamide
Information reviewed July 24, 2026
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What is it for?
A once-daily pill used as part of HIV treatment and for HIV pre-exposure prophylaxis (PrEP) in certain at-risk adults and adolescents.
Primary Condition
HIV treatment and prevention (PrEP)
How it works
Two NRTIs that block the enzyme HIV needs to multiply, lowering the amount of virus in the body.
Common Side Effects
This is not a complete list of side effects. Always consult with a doctor.
- Diarrhea
- Nausea
- Headache
- Worsening of hepatitis B if stopped (boxed warning)
- Not for all PrEP populations
Descovy FAQs
What is Descovy used for?
Descovy (emtricitabine/tenofovir alafenamide) is a prescription medication used to treat HIV treatment and prevention (PrEP). A once-daily pill used as part of HIV treatment and for HIV pre-exposure prophylaxis (PrEP) in certain at-risk adults and adolescents.
How does Descovy work?
Two NRTIs that block the enzyme HIV needs to multiply, lowering the amount of virus in the body.
What are the common side effects of Descovy?
Commonly reported side effects of Descovy include Diarrhea, Nausea, Headache, Worsening of hepatitis B if stopped (boxed warning), and Not for all PrEP populations. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Descovy have any serious warnings?
Yes. Descovy carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
What is the generic name for Descovy?
The active ingredient in Descovy is emtricitabine/tenofovir alafenamide, which belongs to a class of medicines known as NRTI Combination.
Who makes Descovy?
Descovy is manufactured by Gilead Sciences. It was first approved in 2016.
How can I save money on Descovy?
You may be able to lower the cost of Descovy by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.
Common questions about Descovy
Other HIV medications
Biktarvy
bictegravir/emtricitabine/tenofovir alafenamide
Cabenuva
cabotegravir/rilpivirine
Apretude
cabotegravir
Sunlenca
lenacapavir
Quick Facts
Manufacturer
Gilead Sciences
Year Approved
2016
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