Descovy

Black Box Warning

Generic: emtricitabine/tenofovir alafenamide

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Information reviewed July 24, 2026

Rank #121 in US TV Ads
Class: NRTI Combination

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What is it for?

A once-daily pill used as part of HIV treatment and for HIV pre-exposure prophylaxis (PrEP) in certain at-risk adults and adolescents.

Primary Condition

HIV treatment and prevention (PrEP)

How it works

Two NRTIs that block the enzyme HIV needs to multiply, lowering the amount of virus in the body.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Diarrhea
  • Nausea
  • Headache
  • Worsening of hepatitis B if stopped (boxed warning)
  • Not for all PrEP populations

Descovy FAQs

What is Descovy used for?

Descovy (emtricitabine/tenofovir alafenamide) is a prescription medication used to treat HIV treatment and prevention (PrEP). A once-daily pill used as part of HIV treatment and for HIV pre-exposure prophylaxis (PrEP) in certain at-risk adults and adolescents.

How does Descovy work?

Two NRTIs that block the enzyme HIV needs to multiply, lowering the amount of virus in the body.

What are the common side effects of Descovy?

Commonly reported side effects of Descovy include Diarrhea, Nausea, Headache, Worsening of hepatitis B if stopped (boxed warning), and Not for all PrEP populations. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Descovy have any serious warnings?

Yes. Descovy carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Descovy?

The active ingredient in Descovy is emtricitabine/tenofovir alafenamide, which belongs to a class of medicines known as NRTI Combination.

Who makes Descovy?

Descovy is manufactured by Gilead Sciences. It was first approved in 2016.

How can I save money on Descovy?

You may be able to lower the cost of Descovy by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Descovy

Other HIV medications

See more drugs like Descovy

Quick Facts

Manufacturer

Gilead Sciences

Year Approved

2016

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