Kesimpta

Moderate Warnings

Generic: ofatumumab

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Information reviewed July 24, 2026

Rank #139 in US TV Ads
Class: Anti-CD20 Monoclonal Antibody

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What is it for?

A once-monthly at-home self-injection pen for relapsing forms of multiple sclerosis.

Primary Condition

Multiple sclerosis

How it works

An anti-CD20 monoclonal antibody that targets and reduces B-cells involved in the immune attack on nerves in MS.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Injection reactions
  • Upper respiratory infections
  • Headache
  • Increased infection risk

Kesimpta FAQs

What is Kesimpta used for?

Kesimpta (ofatumumab) is a prescription medication used to treat Multiple sclerosis. A once-monthly at-home self-injection pen for relapsing forms of multiple sclerosis.

How does Kesimpta work?

An anti-CD20 monoclonal antibody that targets and reduces B-cells involved in the immune attack on nerves in MS.

What are the common side effects of Kesimpta?

Commonly reported side effects of Kesimpta include Injection reactions, Upper respiratory infections, Headache, and Increased infection risk. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Kesimpta have any serious warnings?

Kesimpta has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Kesimpta.

What is the generic name for Kesimpta?

The active ingredient in Kesimpta is ofatumumab, which belongs to a class of medicines known as Anti-CD20 Monoclonal Antibody.

Who makes Kesimpta?

Kesimpta is manufactured by Novartis. It was first approved in 2020.

How can I save money on Kesimpta?

You may be able to lower the cost of Kesimpta by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Kesimpta

Other Neurology medications

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Quick Facts

Manufacturer

Novartis

Year Approved

2020

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