Litfulo

Black Box Warning

Generic: ritlecitinib

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Information reviewed July 24, 2026

Rank #67 in US TV Ads
Class: JAK3/TEC Inhibitor

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What is it for?

A once-daily pill for severe alopecia areata that can help regrow scalp hair in adolescents and adults.

Primary Condition

Severe alopecia areata

How it works

Blocks JAK3 and TEC enzymes involved in the immune attack on hair follicles.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Serious infections
  • Blood clots
  • Increased cancer risk
  • Headache
  • Diarrhea

Litfulo FAQs

What is Litfulo used for?

Litfulo (ritlecitinib) is a prescription medication used to treat Severe alopecia areata. A once-daily pill for severe alopecia areata that can help regrow scalp hair in adolescents and adults.

How does Litfulo work?

Blocks JAK3 and TEC enzymes involved in the immune attack on hair follicles.

What are the common side effects of Litfulo?

Commonly reported side effects of Litfulo include Serious infections, Blood clots, Increased cancer risk, Headache, and Diarrhea. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Litfulo have any serious warnings?

Yes. Litfulo carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Litfulo?

The active ingredient in Litfulo is ritlecitinib, which belongs to a class of medicines known as JAK3/TEC Inhibitor.

Who makes Litfulo?

Litfulo is manufactured by Pfizer. It was first approved in 2023.

How can I save money on Litfulo?

You may be able to lower the cost of Litfulo by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Litfulo

Other Autoimmune medications

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Quick Facts

Manufacturer

Pfizer

Year Approved

2023

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