Nexletol

Moderate Warnings

Generic: bempedoic acid

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Information reviewed July 24, 2026

Rank #142 in US TV Ads
Class: ATP Citrate Lyase Inhibitor

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What is it for?

An oral non-statin pill that lowers LDL (bad) cholesterol, often used by people who can't tolerate or need more help than statins alone.

Primary Condition

High cholesterol

How it works

An ATP citrate lyase inhibitor that reduces the liver's production of cholesterol.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Muscle spasms
  • Gout
  • Higher uric acid
  • Tendon rupture risk
  • Upper respiratory infection

Nexletol FAQs

What is Nexletol used for?

Nexletol (bempedoic acid) is a prescription medication used to treat High cholesterol. An oral non-statin pill that lowers LDL (bad) cholesterol, often used by people who can't tolerate or need more help than statins alone.

How does Nexletol work?

An ATP citrate lyase inhibitor that reduces the liver's production of cholesterol.

What are the common side effects of Nexletol?

Commonly reported side effects of Nexletol include Muscle spasms, Gout, Higher uric acid, Tendon rupture risk, and Upper respiratory infection. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Nexletol have any serious warnings?

Nexletol has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Nexletol.

What is the generic name for Nexletol?

The active ingredient in Nexletol is bempedoic acid, which belongs to a class of medicines known as ATP Citrate Lyase Inhibitor.

Who makes Nexletol?

Nexletol is manufactured by Esperion. It was first approved in 2020.

How can I save money on Nexletol?

You may be able to lower the cost of Nexletol by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Nexletol

Other Cardiovascular medications

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Quick Facts

Manufacturer

Esperion

Year Approved

2020

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