Nucala

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Generic: mepolizumab

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Information reviewed July 24, 2026

Rank #75 in US TV Ads
Class: IL-5 Antagonist (Biologic)

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What is it for?

An add-on injection for severe eosinophilic asthma and several related inflammatory conditions.

Primary Condition

Severe eosinophilic asthma, COPD, nasal polyps

How it works

Blocks IL-5 to lower eosinophils, reducing airway inflammation and flare-ups.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Headache
  • Injection site reactions
  • Back pain
  • Fatigue
  • Allergic reactions

Nucala FAQs

What is Nucala used for?

Nucala (mepolizumab) is a prescription medication used to treat Severe eosinophilic asthma, COPD, nasal polyps. An add-on injection for severe eosinophilic asthma and several related inflammatory conditions.

How does Nucala work?

Blocks IL-5 to lower eosinophils, reducing airway inflammation and flare-ups.

What are the common side effects of Nucala?

Commonly reported side effects of Nucala include Headache, Injection site reactions, Back pain, Fatigue, and Allergic reactions. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Nucala have any serious warnings?

Nucala does not carry an FDA Boxed Warning, but every prescription medicine has risks and possible interactions. Always follow your doctor's instructions and read the medication guide that comes with it.

What is the generic name for Nucala?

The active ingredient in Nucala is mepolizumab, which belongs to a class of medicines known as IL-5 Antagonist (Biologic).

Who makes Nucala?

Nucala is manufactured by GSK. It was first approved in 2015.

How can I save money on Nucala?

You may be able to lower the cost of Nucala by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Nucala

Other Respiratory medications

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Quick Facts

Manufacturer

GSK

Year Approved

2015

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