Opdivo

Moderate Warnings

Generic: nivolumab

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Information reviewed July 24, 2026

Rank #25 in US TV Ads
Class: PD-1 Inhibitor (Immunotherapy)

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What is it for?

An immunotherapy for cancers such as melanoma, lung, kidney, and others, used alone or combined with other treatments.

Primary Condition

Multiple cancers

How it works

Blocks the PD-1 checkpoint so the immune system is no longer suppressed by cancer cells and can attack the tumor.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Immune-related side effects
  • Fatigue
  • Rash
  • Diarrhea
  • Pneumonitis
  • Thyroid problems

Opdivo FAQs

What is Opdivo used for?

Opdivo (nivolumab) is a prescription medication used to treat Multiple cancers. An immunotherapy for cancers such as melanoma, lung, kidney, and others, used alone or combined with other treatments.

How does Opdivo work?

Blocks the PD-1 checkpoint so the immune system is no longer suppressed by cancer cells and can attack the tumor.

What are the common side effects of Opdivo?

Commonly reported side effects of Opdivo include Immune-related side effects, Fatigue, Rash, Diarrhea, Pneumonitis, and Thyroid problems. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Opdivo have any serious warnings?

Opdivo has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Opdivo.

What is the generic name for Opdivo?

The active ingredient in Opdivo is nivolumab, which belongs to a class of medicines known as PD-1 Inhibitor (Immunotherapy).

Who makes Opdivo?

Opdivo is manufactured by Bristol-Myers Squibb. It was first approved in 2014.

How can I save money on Opdivo?

You may be able to lower the cost of Opdivo by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Opdivo

Other Oncology medications

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Quick Facts

Manufacturer

Bristol-Myers Squibb

Year Approved

2014

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