Rinvoq

Black Box Warning

Generic: upadacitinib

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Information reviewed July 24, 2026

Rank #10 in US TV Ads
Class: JAK Inhibitor

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What is it for?

Rinvoq is an oral JAK inhibitor used for adults with moderately to severely active rheumatoid arthritis, psoriatic arthritis, and eczema who have not responded adequately to other treatments.

Primary Condition

Rheumatoid arthritis, psoriatic arthritis, eczema

How it works

Rinvoq inhibits Janus kinase (JAK) enzymes, which are involved in the signaling pathways that drive inflammation. By blocking JAK enzymes, Rinvoq reduces the inflammatory signals that cause joint damage and skin symptoms.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Serious infections
  • Blood clots
  • Cardiovascular events
  • Cancer risk
  • Liver problems
  • Decreased blood counts

Rinvoq FAQs

What is Rinvoq used for?

Rinvoq (upadacitinib) is a prescription medication used to treat Rheumatoid arthritis, psoriatic arthritis, eczema. Rinvoq is an oral JAK inhibitor used for adults with moderately to severely active rheumatoid arthritis, psoriatic arthritis, and eczema who have not responded adequately to other treatments.

How does Rinvoq work?

Rinvoq inhibits Janus kinase (JAK) enzymes, which are involved in the signaling pathways that drive inflammation. By blocking JAK enzymes, Rinvoq reduces the inflammatory signals that cause joint damage and skin symptoms.

What are the common side effects of Rinvoq?

Commonly reported side effects of Rinvoq include Serious infections, Blood clots, Cardiovascular events, Cancer risk, Liver problems, and Decreased blood counts. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Rinvoq have any serious warnings?

Yes. Rinvoq carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Rinvoq?

The active ingredient in Rinvoq is upadacitinib, which belongs to a class of medicines known as JAK Inhibitor.

Who makes Rinvoq?

Rinvoq is manufactured by AbbVie. It was first approved in 2019.

How can I save money on Rinvoq?

You may be able to lower the cost of Rinvoq by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Rinvoq

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Quick Facts

Manufacturer

AbbVie

Year Approved

2019

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