Stelara

Moderate Warnings

Generic: ustekinumab

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Information reviewed July 24, 2026

Rank #20 in US TV Ads
Class: IL-12/IL-23 Inhibitor (Biologic)

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What is it for?

A biologic that treats plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis.

Primary Condition

Psoriasis, Crohn's disease, ulcerative colitis

How it works

Blocks two cytokines, IL-12 and IL-23, that drive the inflammatory immune response in psoriasis and inflammatory bowel disease.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Serious infections
  • Headache
  • Fatigue
  • Injection site reactions
  • Cancer risk

Stelara FAQs

What is Stelara used for?

Stelara (ustekinumab) is a prescription medication used to treat Psoriasis, Crohn's disease, ulcerative colitis. A biologic that treats plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis.

How does Stelara work?

Blocks two cytokines, IL-12 and IL-23, that drive the inflammatory immune response in psoriasis and inflammatory bowel disease.

What are the common side effects of Stelara?

Commonly reported side effects of Stelara include Serious infections, Headache, Fatigue, Injection site reactions, and Cancer risk. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Stelara have any serious warnings?

Stelara has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Stelara.

What is the generic name for Stelara?

The active ingredient in Stelara is ustekinumab, which belongs to a class of medicines known as IL-12/IL-23 Inhibitor (Biologic).

Who makes Stelara?

Stelara is manufactured by Janssen. It was first approved in 2009.

How can I save money on Stelara?

You may be able to lower the cost of Stelara by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Stelara

Other Autoimmune medications

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Quick Facts

Manufacturer

Janssen

Year Approved

2009

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