Syfovre

Moderate Warnings

Generic: pegcetacoplan

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Information reviewed July 24, 2026

Rank #113 in US TV Ads
Class: Complement C3 Inhibitor

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What is it for?

An eye injection for geographic atrophy, an advanced form of dry age-related macular degeneration that destroys central vision.

Primary Condition

Geographic atrophy (advanced dry AMD)

How it works

A complement C3 inhibitor that slows the immune-driven breakdown of light-sensing cells in the retina.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Eye discomfort
  • Floaters
  • Bleeding in the eye
  • Increased eye pressure
  • Risk of eye infection

Syfovre FAQs

What is Syfovre used for?

Syfovre (pegcetacoplan) is a prescription medication used to treat Geographic atrophy (advanced dry AMD). An eye injection for geographic atrophy, an advanced form of dry age-related macular degeneration that destroys central vision.

How does Syfovre work?

A complement C3 inhibitor that slows the immune-driven breakdown of light-sensing cells in the retina.

What are the common side effects of Syfovre?

Commonly reported side effects of Syfovre include Eye discomfort, Floaters, Bleeding in the eye, Increased eye pressure, and Risk of eye infection. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Syfovre have any serious warnings?

Syfovre has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Syfovre.

What is the generic name for Syfovre?

The active ingredient in Syfovre is pegcetacoplan, which belongs to a class of medicines known as Complement C3 Inhibitor.

Who makes Syfovre?

Syfovre is manufactured by Apellis Pharmaceuticals. It was first approved in 2023.

How can I save money on Syfovre?

You may be able to lower the cost of Syfovre by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Syfovre

Other Eye Health medications

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Quick Facts

Manufacturer

Apellis Pharmaceuticals

Year Approved

2023

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