Tremfya

Moderate Warnings

Generic: guselkumab

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Information reviewed July 24, 2026

Rank #19 in US TV Ads
Class: IL-23 Inhibitor (Biologic)

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What is it for?

A biologic for moderate-to-severe plaque psoriasis and psoriatic arthritis given as an injection every eight weeks after starter doses.

Primary Condition

Plaque psoriasis, psoriatic arthritis

How it works

Blocks interleukin-23 (IL-23) to interrupt the inflammatory cascade that produces psoriasis plaques and joint inflammation.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Respiratory infections
  • Headache
  • Injection site reactions
  • Joint pain
  • Diarrhea

Tremfya FAQs

What is Tremfya used for?

Tremfya (guselkumab) is a prescription medication used to treat Plaque psoriasis, psoriatic arthritis. A biologic for moderate-to-severe plaque psoriasis and psoriatic arthritis given as an injection every eight weeks after starter doses.

How does Tremfya work?

Blocks interleukin-23 (IL-23) to interrupt the inflammatory cascade that produces psoriasis plaques and joint inflammation.

What are the common side effects of Tremfya?

Commonly reported side effects of Tremfya include Respiratory infections, Headache, Injection site reactions, Joint pain, and Diarrhea. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Tremfya have any serious warnings?

Tremfya has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Tremfya.

What is the generic name for Tremfya?

The active ingredient in Tremfya is guselkumab, which belongs to a class of medicines known as IL-23 Inhibitor (Biologic).

Who makes Tremfya?

Tremfya is manufactured by Janssen. It was first approved in 2017.

How can I save money on Tremfya?

You may be able to lower the cost of Tremfya by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Tremfya

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Quick Facts

Manufacturer

Janssen

Year Approved

2017

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