Vraylar

Black Box Warning

Generic: cariprazine

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Information reviewed July 24, 2026

Rank #28 in US TV Ads
Class: Atypical Antipsychotic

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What is it for?

An oral antipsychotic for bipolar I disorder and schizophrenia, also used as an add-on treatment for major depression.

Primary Condition

Bipolar disorder, schizophrenia, depression (add-on)

How it works

Partially modulates dopamine D2/D3 and serotonin receptors to help balance mood and thinking.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Movement disorders
  • Drowsiness
  • Restlessness
  • Weight changes
  • Increased mortality in dementia patients

Vraylar FAQs

What is Vraylar used for?

Vraylar (cariprazine) is a prescription medication used to treat Bipolar disorder, schizophrenia, depression (add-on). An oral antipsychotic for bipolar I disorder and schizophrenia, also used as an add-on treatment for major depression.

How does Vraylar work?

Partially modulates dopamine D2/D3 and serotonin receptors to help balance mood and thinking.

What are the common side effects of Vraylar?

Commonly reported side effects of Vraylar include Movement disorders, Drowsiness, Restlessness, Weight changes, and Increased mortality in dementia patients. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Vraylar have any serious warnings?

Yes. Vraylar carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Vraylar?

The active ingredient in Vraylar is cariprazine, which belongs to a class of medicines known as Atypical Antipsychotic.

Who makes Vraylar?

Vraylar is manufactured by AbbVie. It was first approved in 2015.

How can I save money on Vraylar?

You may be able to lower the cost of Vraylar by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Vraylar

Other Mental Health medications

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Quick Facts

Manufacturer

AbbVie

Year Approved

2015

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