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What is it for?
An oral pill for several autoimmune conditions when other treatments have not worked well enough.
Primary Condition
Rheumatoid arthritis, psoriatic arthritis, ulcerative colitis
How it works
Blocks JAK enzymes that carry inflammatory signals inside immune cells.
Common Side Effects
This is not a complete list of side effects. Always consult with a doctor.
- Serious infections
- Blood clots
- Increased cancer risk
- Heart-related events
- Increased cholesterol
Xeljanz FAQs
What is Xeljanz used for?
Xeljanz (tofacitinib) is a prescription medication used to treat Rheumatoid arthritis, psoriatic arthritis, ulcerative colitis. An oral pill for several autoimmune conditions when other treatments have not worked well enough.
How does Xeljanz work?
Blocks JAK enzymes that carry inflammatory signals inside immune cells.
What are the common side effects of Xeljanz?
Commonly reported side effects of Xeljanz include Serious infections, Blood clots, Increased cancer risk, Heart-related events, and Increased cholesterol. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Xeljanz have any serious warnings?
Yes. Xeljanz carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
What is the generic name for Xeljanz?
The active ingredient in Xeljanz is tofacitinib, which belongs to a class of medicines known as JAK Inhibitor.
Who makes Xeljanz?
Xeljanz is manufactured by Pfizer. It was first approved in 2012.
How can I save money on Xeljanz?
You may be able to lower the cost of Xeljanz by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.
Common questions about Xeljanz
Other Autoimmune medications
Humira
adalimumab
Skyrizi
risankizumab
Dupixent
dupilumab
Taltz
ixekizumab
Rinvoq
upadacitinib
Cosentyx
secukinumab
Quick Facts
Manufacturer
Pfizer
Year Approved
2012
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