Xiidra

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Generic: lifitegrast

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Information reviewed July 24, 2026

Rank #58 in US TV Ads
Class: LFA-1 Antagonist (Eye Drop)

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What is it for?

A prescription eye drop, advertised heavily on TV, that treats both the signs and symptoms of chronic dry eye.

Primary Condition

Dry eye disease

How it works

Blocks a protein interaction (LFA-1/ICAM-1) involved in the inflammation that drives dry eye disease.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Eye irritation
  • Unusual taste
  • Blurred vision
  • Eye discomfort on application

Xiidra FAQs

What is Xiidra used for?

Xiidra (lifitegrast) is a prescription medication used to treat Dry eye disease. A prescription eye drop, advertised heavily on TV, that treats both the signs and symptoms of chronic dry eye.

How does Xiidra work?

Blocks a protein interaction (LFA-1/ICAM-1) involved in the inflammation that drives dry eye disease.

What are the common side effects of Xiidra?

Commonly reported side effects of Xiidra include Eye irritation, Unusual taste, Blurred vision, and Eye discomfort on application. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Xiidra have any serious warnings?

Xiidra does not carry an FDA Boxed Warning, but every prescription medicine has risks and possible interactions. Always follow your doctor's instructions and read the medication guide that comes with it.

What is the generic name for Xiidra?

The active ingredient in Xiidra is lifitegrast, which belongs to a class of medicines known as LFA-1 Antagonist (Eye Drop).

Who makes Xiidra?

Xiidra is manufactured by Bausch + Lomb. It was first approved in 2016.

How can I save money on Xiidra?

You may be able to lower the cost of Xiidra by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Xiidra

Other Eye Health medications

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Quick Facts

Manufacturer

Bausch + Lomb

Year Approved

2016

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