Biktarvy vs Apretude

A side-by-side look at two hiv medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US BiktarvyUS Apretude
Generic namebictegravir/emtricitabine/tenofovir alafenamidecabotegravir
Drug classIntegrase Inhibitor + NRTI CombinationIntegrase Inhibitor (Long-Acting Injectable PrEP)
TreatsHIV-1 infectionHIV prevention (PrEP)
CategoryHIVHIV
ManufacturerGilead SciencesViiV Healthcare
Year approved20182021
FDA warningBlack box warningModerate warnings
Est. TV ad spend$180M
Common side effectsWorsening of hepatitis B after stopping, Headache, Diarrhea, NauseaInjection site reactions, Headache, Fever, Fatigue

Frequently asked questions

Is Biktarvy or Apretude better?

Neither is universally "better." Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) and Apretude (cabotegravir) are both used for hiv, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Biktarvy and Apretude?

Biktarvy is a Integrase Inhibitor + NRTI Combination made by Gilead Sciences, while Apretude is a Integrase Inhibitor (Long-Acting Injectable PrEP) made by ViiV Healthcare. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Biktarvy has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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