Combined Ad Spend
$13.1B
Advertisers Ranked
144
- 1
Humira
USadalimumab · Rheumatoid arthritis, psoriasis, Crohn's disease
$500M
est. / yr
- 2
Skyrizi
USrisankizumab · Plaque psoriasis, psoriatic arthritis, Crohn's disease
$480M
est. / yr
- 3
Ozempic
USsemaglutide · Type 2 diabetes
$420M
est. / yr
- 4
Dupixent
USdupilumab · Eczema, asthma, nasal polyps
$390M
est. / yr
- 5
Wegovy
USsemaglutide · Chronic weight management, cardiovascular risk reduction
$380M
est. / yr
- 6
Eliquis
USapixaban · Blood clots, atrial fibrillation
$350M
est. / yr
- 7
Mounjaro
UStirzepatide · Type 2 diabetes
$350M
est. / yr
- 8
Zepbound
UStirzepatide · Chronic weight management, obstructive sleep apnea
$300M
est. / yr
- 9
Jardiance
USempagliflozin · Type 2 diabetes, heart failure, chronic kidney disease
$280M
est. / yr
- 10
Keytruda
USpembrolizumab · Multiple cancers
$260M
est. / yr
- 11
Trulicity
USdulaglutide · Type 2 diabetes
$240M
est. / yr
- 12
Farxiga
USdapagliflozin · Type 2 diabetes, heart failure, chronic kidney disease
$220M
est. / yr
- 13
Xarelto
USrivaroxaban · Blood clots, atrial fibrillation
$210M
est. / yr
- 14
Vraylar
UScariprazine · Bipolar disorder, schizophrenia, depression (add-on)
$200M
est. / yr
- 15
Trelegy Ellipta
USfluticasone/umeclidinium/vilanterol · COPD, asthma
$200M
est. / yr
- 16
Taltz
USixekizumab · Plaque psoriasis, psoriatic arthritis, ankylosing spondylitis
$190M
est. / yr
- 17
Nurtec ODT
USrimegepant · Migraine (acute and preventive)
$190M
est. / yr
- 18
Rybelsus
USsemaglutide · Type 2 diabetes
$180M
est. / yr
- 19
Biktarvy
USbictegravir/emtricitabine/tenofovir alafenamide · HIV-1 infection
$180M
est. / yr
- 20
Rinvoq
USupadacitinib · Rheumatoid arthritis, psoriatic arthritis, eczema
$175M
est. / yr
- 21
Rexulti
USbrexpiprazole · Major depression (add-on), schizophrenia, agitation in dementia
$170M
est. / yr
- 22
Cosentyx
USsecukinumab · Plaque psoriasis, psoriatic arthritis, ankylosing spondylitis
$160M
est. / yr
- 23
Ubrelvy
USubrogepant · Acute migraine
$160M
est. / yr
- 24
Entresto
USsacubitril/valsartan · Chronic heart failure
$150M
est. / yr
- 25
Opdivo
USnivolumab · Multiple cancers
$150M
est. / yr
- 26
Austedo
USdeutetrabenazine · Tardive dyskinesia, Huntington's chorea
$150M
est. / yr
- 27
Xiidra
USlifitegrast · Dry eye disease
$150M
est. / yr
- 28
Shingrix
USrecombinant zoster vaccine · Shingles prevention
$150M
est. / yr
- 29
Tremfya
USguselkumab · Plaque psoriasis, psoriatic arthritis
$140M
est. / yr
- 30
Linzess
USlinaclotide · Irritable bowel syndrome with constipation, chronic constipation
$140M
est. / yr
- 31
Myrbetriq
USmirabegron · Overactive bladder
$140M
est. / yr
- 32
Stelara
USustekinumab · Psoriasis, Crohn's disease, ulcerative colitis
$130M
est. / yr
- 33
Caplyta
USlumateperone · Schizophrenia, bipolar depression
$130M
est. / yr
- 34
Trintellix
USvortioxetine · Major depressive disorder
$130M
est. / yr
- 35
Xifaxan
USrifaximin · Irritable bowel syndrome with diarrhea, hepatic encephalopathy
$130M
est. / yr
- 36
Sotyktu
USdeucravacitinib · Plaque psoriasis
$130M
est. / yr
- 37
Repatha
USevolocumab · High cholesterol, cardiovascular disease
$120M
est. / yr
- 38
Qulipta
USatogepant · Migraine prevention
$120M
est. / yr
- 39
Breztri Aerosphere
USbudesonide/glycopyrrolate/formoterol · COPD
$120M
est. / yr
- 40
Brilinta
USticagrelor · Acute coronary syndrome, heart attack prevention
$120M
est. / yr
- 41
Prolia
USdenosumab · Osteoporosis
$120M
est. / yr
- 42
Symbicort
USbudesonide/formoterol · Asthma, COPD
$120M
est. / yr
- 43
Otezla
USapremilast · Plaque psoriasis, psoriatic arthritis, Behçet's disease
$110M
est. / yr
- 44
Veozah
USfezolinetant · Menopausal hot flashes
$110M
est. / yr
- 45
Invokana
UScanagliflozin · Type 2 diabetes, diabetic kidney disease
$110M
est. / yr
- 46
Emgality
USgalcanezumab · Migraine prevention, cluster headache
$110M
est. / yr
- 47
Arexvy
USrespiratory syncytial virus vaccine · RSV prevention in older adults
$110M
est. / yr
- 48
Restasis
UScyclosporine ophthalmic emulsion · Chronic dry eye
$100M
est. / yr
- 49
Aimovig
USerenumab · Migraine prevention
$100M
est. / yr
- 50
Breo Ellipta
USfluticasone/vilanterol · Asthma, COPD
$100M
est. / yr
- 51
Cialis
UStadalafil · Erectile dysfunction, enlarged prostate (BPH)
$100M
est. / yr
- 52
Humira
CAadalimumab · Rheumatoid arthritis, psoriasis, Crohn's disease
$95M
est. / yr
- 53
Entyvio
USvedolizumab · Ulcerative colitis, Crohn's disease
$95M
est. / yr
- 54
Xolair
USomalizumab · Allergic asthma, chronic hives, food allergy
$95M
est. / yr
- 55
Dovato
USdolutegravir/lamivudine · HIV-1 infection
$95M
est. / yr
- 56
Leqvio
USinclisiran · High cholesterol, cardiovascular disease
$90M
est. / yr
- 57
Vascepa
USicosapent ethyl · High triglycerides, cardiovascular risk reduction
$90M
est. / yr
- 58
Eylea
USaflibercept · Wet macular degeneration, diabetic eye disease
$90M
est. / yr
- 59
Xeljanz
UStofacitinib · Rheumatoid arthritis, psoriatic arthritis, ulcerative colitis
$90M
est. / yr
- 60
Chantix
USvarenicline · Smoking cessation
$90M
est. / yr
- 61
Xtandi
USenzalutamide · Prostate cancer
$90M
est. / yr
- 62
Ozempic
CAsemaglutide · Type 2 diabetes
$85M
est. / yr
- 63
Verzenio
USabemaciclib · HR+/HER2- breast cancer
$85M
est. / yr
- 64
Vabysmo
USfaricimab · Wet macular degeneration, diabetic macular edema
$85M
est. / yr
- 65
Latuda
USlurasidone · Schizophrenia, bipolar depression
$85M
est. / yr
- 66
Ibrance
USpalbociclib · HR+/HER2- breast cancer
$80M
est. / yr
- 67
Gemtesa
USvibegron · Overactive bladder
$80M
est. / yr
- 68
Fasenra
USbenralizumab · Severe eosinophilic asthma
$80M
est. / yr
- 69
Mavyret
USglecaprevir/pibrentasvir · Hepatitis C
$80M
est. / yr
- 70
Kisqali
USribociclib · HR-positive, HER2-negative breast cancer
$80M
est. / yr
- 71
Eliquis
CAapixaban · Blood clots, atrial fibrillation
$75M
est. / yr
- 72
Cibinqo
USabrocitinib · Atopic dermatitis (eczema)
$75M
est. / yr
- 73
Nucala
USmepolizumab · Severe eosinophilic asthma, COPD, nasal polyps
$75M
est. / yr
- 74
Quviviq
USdaridorexant · Insomnia
$75M
est. / yr
- 75
Vuity
USpilocarpine ophthalmic · Age-related blurry near vision (presbyopia)
$70M
est. / yr
- 76
Evenity
USromosozumab · Osteoporosis (high fracture risk)
$70M
est. / yr
- 77
Ajovy
USfremanezumab · Migraine prevention
$70M
est. / yr
- 78
Tezspire
UStezepelumab · Severe asthma
$70M
est. / yr
- 79
Vyvanse
USlisdexamfetamine · ADHD, binge eating disorder
$70M
est. / yr
- 80
Dupixent
CAdupilumab · Eczema, asthma, nasal polyps
$65M
est. / yr
- 81
Litfulo
USritlecitinib · Severe alopecia areata
$65M
est. / yr
- 82
Lipitor
USatorvastatin · High cholesterol, cardiovascular prevention
$60M
est. / yr
- 83
Kerendia
USfinerenone · Chronic kidney disease in type 2 diabetes
$60M
est. / yr
- 84
Olumiant
USbaricitinib · Rheumatoid arthritis, severe alopecia areata
$60M
est. / yr
- 85
Paxlovid
USnirmatrelvir/ritonavir · COVID-19 (mild to moderate)
$60M
est. / yr
- 86
Orilissa
USelagolix · Endometriosis pain
$60M
est. / yr
- 87
Jardiance
CAempagliflozin · Type 2 diabetes, heart failure, chronic kidney disease
$55M
est. / yr
- 88
Bimzelx
USbimekizumab · Plaque psoriasis, psoriatic arthritis
$55M
est. / yr
- 89
Auvelity
USdextromethorphan/bupropion · Major depressive disorder
$50M
est. / yr
- 90
Skyrizi
CArisankizumab · Plaque psoriasis, psoriatic arthritis, Crohn's disease
$48M
est. / yr
- 91
Crestor
USrosuvastatin · High cholesterol, cardiovascular prevention
$45M
est. / yr
- 92
Keytruda
CApembrolizumab · Multiple cancers
$42M
est. / yr
- 93
Mounjaro
CAtirzepatide · Type 2 diabetes
$40M
est. / yr
- 94
Rinvoq
CAupadacitinib · Rheumatoid arthritis, psoriatic arthritis, eczema
$38M
est. / yr
- 95
Repatha
CAevolocumab · High cholesterol, cardiovascular disease
$32M
est. / yr
- 96
Victoza
CAliraglutide · Type 2 diabetes, obesity
$28M
est. / yr
- 97
Xarelto
CArivaroxaban · Blood clots, atrial fibrillation
$28M
est. / yr
- 98
Trulicity
CAdulaglutide · Type 2 diabetes
$26M
est. / yr
- 99
Tylenol
CAacetaminophen · Pain relief, fever
$14M
est. / yr
- 100
Advair
CAfluticasone/salmeterol · Asthma, COPD
$12M
est. / yr
- 101
Voltaren
NZdiclofenac · Arthritis, muscle pain, joint pain
$12M
est. / yr
- 102
Symbicort
CAbudesonide/formoterol · Asthma, COPD
$11M
est. / yr
- 103
Nurofen
NZibuprofen · Pain relief, inflammation, fever
$10M
est. / yr
- 104
Nexium
CAesomeprazole · Acid reflux, GERD, ulcers
$9M
est. / yr
- 105
Lipitor
CAatorvastatin · High cholesterol, cardiovascular prevention
$8M
est. / yr
- 106
Nasonex
NZmometasone · Allergic rhinitis, hay fever, nasal polyps
$8M
est. / yr
- 107
Nicorette
NZnicotine · Smoking cessation
$8M
est. / yr
- 108
Crestor
CArosuvastatin · High cholesterol, cardiovascular prevention
$7M
est. / yr
- 109
Ventolin
CAsalbutamol · Asthma, bronchospasm
$6M
est. / yr
- 110
Nexium
NZesomeprazole · Acid reflux, GERD, stomach ulcers
$6M
est. / yr
- 111
Claratyne
NZloratadine · Hay fever, allergic rhinitis, hives
$6M
est. / yr
- 112
Synthroid
CAlevothyroxine · Hypothyroidism
$5M
est. / yr
- 113
Panadol
NZparacetamol · Pain relief, fever
$5M
est. / yr
- 114
Fosamax
NZalendronate · Osteoporosis
$5M
est. / yr
- 115
Cipralex
CAescitalopram · Depression, anxiety
$4M
est. / yr
- 116
Telfast
NZfexofenadine · Hay fever, allergic rhinitis, hives
$4M
est. / yr
- 117
Champix
NZvarenicline · Smoking cessation
$4M
est. / yr
- 118
Zyrtec
NZcetirizine · Hay fever, allergies, hives
$4M
est. / yr
- 119
Lipitor
NZatorvastatin · High cholesterol, cardiovascular disease prevention
$4M
est. / yr
- 120
Concerta
CAmethylphenidate · ADHD
$3M
est. / yr
- 121
Losec
NZomeprazole · Acid reflux, stomach ulcers, GERD
$3M
est. / yr
- 122
Ozempic
NZsemaglutide · Type 2 diabetes
$3M
est. / yr
- 123
Otrivin
NZxylometazoline · Nasal congestion, cold and sinus relief
$3M
est. / yr
- 124
Ventolin
NZsalbutamol · Asthma, bronchospasm
$3M
est. / yr
- 125
Symbicort
NZbudesonide/formoterol · Asthma, COPD
$3M
est. / yr
- 126
Altace
CAramipril · High blood pressure, heart protection
$2M
est. / yr
- 127
Glucophage
CAmetformin · Type 2 diabetes
$2M
est. / yr
- 128
Pantoloc
CApantoprazole · Acid reflux, GERD, ulcers
$2M
est. / yr
- 129
Seretide
NZfluticasone/salmeterol · Asthma, COPD
$2M
est. / yr
- 130
Jardiance
NZempagliflozin · Type 2 diabetes, heart failure
$2M
est. / yr
- 131
Metformin
USmetformin · Type 2 diabetes
$2M
est. / yr
- 132
Cymbalta
NZduloxetine · Depression, anxiety, nerve pain
$2M
est. / yr
- 133
Glucophage
NZmetformin · Type 2 diabetes
$1M
est. / yr
- 134
Augmentin
NZamoxicillin/clavulanate · Bacterial infections
$1M
est. / yr
- 135
Loxalate
NZescitalopram · Depression, anxiety
$1M
est. / yr
- 136
Mobic
NZmeloxicam · Arthritis, joint inflammation
$1M
est. / yr
- 137
Somac
NZpantoprazole · Acid reflux, GERD, ulcers
$1M
est. / yr
- 138
Lisinopril
USlisinopril · High blood pressure, heart failure
$1M
est. / yr
- 139
Amoxicillin
USamoxicillin · Bacterial infections
$1M
est. / yr
- 140
Gabapentin
USgabapentin · Nerve pain, seizures
$1M
est. / yr
- 141
Adderall
USamphetamine/dextroamphetamine · ADHD, narcolepsy
$1M
est. / yr
- 142
Synthroid
USlevothyroxine · Hypothyroidism
$1M
est. / yr
- 143
Prednisone
USprednisone · Inflammation, autoimmune flares, allergic reactions
$1M
est. / yr
- 144
Zoloft
USsertraline · Depression, anxiety, OCD, PTSD
$1M
est. / yr
TV drug ad spend: frequently asked questions
Which prescription drug spends the most on TV advertising?
Humira has the largest estimated TV ad budget at about $500M a year, making it the biggest TV advertiser among the drugs we track.
How much do prescription drugs spend on TV ads in total?
The 144 TV-advertised drugs on this leaderboard have a combined estimated annual TV ad budget of about $13.1B across the US, Canada, and New Zealand.
Why do drug companies advertise so much on TV?
Prescription drugs are among the most heavily advertised products on American television because direct-to-consumer ads encourage patients to ask their doctors about brand-name medicines — which can drive significant sales for high-priced drugs.
Which countries allow prescription drug ads on TV?
Only the United States and New Zealand allow full direct-to-consumer prescription drug advertising, so nearly all TV drug ad spending happens in those two countries.
About this ranking
Figures are estimated annual TV advertising budgets compiled for reference and may differ from official company reporting. Rankings update as our data is refreshed. This page is for general information only and is not medical or financial advice.
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