Xarelto

Black Box Warning

Generic: rivaroxaban

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Information reviewed July 24, 2026

Rank #8 in US TV Ads
Class: Factor Xa Inhibitor

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What is it for?

Xarelto is an anticoagulant (blood thinner) that reduces the risk of stroke and blood clots in people with non-valvular atrial fibrillation, and treats and prevents deep vein thrombosis and pulmonary embolism.

Primary Condition

Blood clots, atrial fibrillation

How it works

Xarelto directly inhibits Factor Xa, stopping it from converting prothrombin to thrombin — a critical step in blood clot formation. This makes it harder for dangerous clots to form.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Serious bleeding risk
  • Bruising
  • Prolonged bleeding
  • Spinal/epidural blood clots
  • Dizziness

Xarelto FAQs

What is Xarelto used for?

Xarelto (rivaroxaban) is a prescription medication used to treat Blood clots, atrial fibrillation. Xarelto is an anticoagulant (blood thinner) that reduces the risk of stroke and blood clots in people with non-valvular atrial fibrillation, and treats and prevents deep vein thrombosis and pulmonary embolism.

How does Xarelto work?

Xarelto directly inhibits Factor Xa, stopping it from converting prothrombin to thrombin — a critical step in blood clot formation. This makes it harder for dangerous clots to form.

What are the common side effects of Xarelto?

Commonly reported side effects of Xarelto include Serious bleeding risk, Bruising, Prolonged bleeding, Spinal/epidural blood clots, and Dizziness. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Xarelto have any serious warnings?

Yes. Xarelto carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Xarelto?

The active ingredient in Xarelto is rivaroxaban, which belongs to a class of medicines known as Factor Xa Inhibitor.

Who makes Xarelto?

Xarelto is manufactured by Janssen/Bayer. It was first approved in 2011.

How can I save money on Xarelto?

You may be able to lower the cost of Xarelto by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Xarelto

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Quick Facts

Manufacturer

Janssen/Bayer

Year Approved

2011

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