Zepbound

Black Box Warning

Generic: tirzepatide

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Information reviewed July 24, 2026

Rank #6 in US TV Ads
Class: GIP/GLP-1 Receptor Agonist

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What is it for?

Tirzepatide approved for chronic weight management and moderate-to-severe obstructive sleep apnea in adults with obesity.

Primary Condition

Chronic weight management, obstructive sleep apnea

How it works

Activates GIP and GLP-1 receptors to curb appetite and increase satiety, driving substantial weight loss.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Injection site reactions
  • Thyroid tumor risk

Zepbound FAQs

What is Zepbound used for?

Zepbound (tirzepatide) is a prescription medication used to treat Chronic weight management, obstructive sleep apnea. Tirzepatide approved for chronic weight management and moderate-to-severe obstructive sleep apnea in adults with obesity.

How does Zepbound work?

Activates GIP and GLP-1 receptors to curb appetite and increase satiety, driving substantial weight loss.

What are the common side effects of Zepbound?

Commonly reported side effects of Zepbound include Nausea, Diarrhea, Vomiting, Constipation, Injection site reactions, and Thyroid tumor risk. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Zepbound have any serious warnings?

Yes. Zepbound carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Zepbound?

The active ingredient in Zepbound is tirzepatide, which belongs to a class of medicines known as GIP/GLP-1 Receptor Agonist.

Who makes Zepbound?

Zepbound is manufactured by Eli Lilly. It was first approved in 2023.

How can I save money on Zepbound?

You may be able to lower the cost of Zepbound by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Zepbound

Other Weight Management medications

See more drugs like Zepbound

Quick Facts

Manufacturer

Eli Lilly

Year Approved

2023

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