Repatha

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Generic: evolocumab

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Information reviewed July 24, 2026

Rank #14 in US TV Ads
Class: PCSK9 Inhibitor (Biologic)

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What is it for?

An injectable that dramatically lowers LDL (bad) cholesterol in people who cannot reach goals with statins alone.

Primary Condition

High cholesterol, cardiovascular disease

How it works

A PCSK9 inhibitor that keeps more LDL receptors active on the liver so it removes more LDL cholesterol from the blood.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Injection site reactions
  • Allergic reactions
  • Back pain
  • Fatigue
  • Flu symptoms

Repatha FAQs

What is Repatha used for?

Repatha (evolocumab) is a prescription medication used to treat High cholesterol, cardiovascular disease. An injectable that dramatically lowers LDL (bad) cholesterol in people who cannot reach goals with statins alone.

How does Repatha work?

A PCSK9 inhibitor that keeps more LDL receptors active on the liver so it removes more LDL cholesterol from the blood.

What are the common side effects of Repatha?

Commonly reported side effects of Repatha include Injection site reactions, Allergic reactions, Back pain, Fatigue, and Flu symptoms. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Repatha have any serious warnings?

Repatha does not carry an FDA Boxed Warning, but every prescription medicine has risks and possible interactions. Always follow your doctor's instructions and read the medication guide that comes with it.

What is the generic name for Repatha?

The active ingredient in Repatha is evolocumab, which belongs to a class of medicines known as PCSK9 Inhibitor (Biologic).

Who makes Repatha?

Repatha is manufactured by Amgen. It was first approved in 2015.

How can I save money on Repatha?

You may be able to lower the cost of Repatha by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Repatha

Other Cardiovascular medications

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Quick Facts

Manufacturer

Amgen

Year Approved

2015

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