Eliquis

Black Box Warning

Generic: apixaban

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Information reviewed July 24, 2026

Rank #5 in US TV Ads
Class: Factor Xa Inhibitor

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What is it for?

Eliquis is a blood thinner (anticoagulant) used to reduce the risk of stroke and blood clots in people with non-valvular atrial fibrillation, and to treat deep vein thrombosis and pulmonary embolism.

Primary Condition

Blood clots, atrial fibrillation

How it works

Eliquis blocks Factor Xa, a key protein in the blood clotting cascade. By inhibiting this factor, it prevents the formation of dangerous blood clots that can cause strokes or blockages in veins.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Serious bleeding risk
  • Bruising easily
  • Prolonged bleeding from cuts
  • Blood in urine or stool
  • Dizziness

Eliquis FAQs

What is Eliquis used for?

Eliquis (apixaban) is a prescription medication used to treat Blood clots, atrial fibrillation. Eliquis is a blood thinner (anticoagulant) used to reduce the risk of stroke and blood clots in people with non-valvular atrial fibrillation, and to treat deep vein thrombosis and pulmonary embolism.

How does Eliquis work?

Eliquis blocks Factor Xa, a key protein in the blood clotting cascade. By inhibiting this factor, it prevents the formation of dangerous blood clots that can cause strokes or blockages in veins.

What are the common side effects of Eliquis?

Commonly reported side effects of Eliquis include Serious bleeding risk, Bruising easily, Prolonged bleeding from cuts, Blood in urine or stool, and Dizziness. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Eliquis have any serious warnings?

Yes. Eliquis carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Eliquis?

The active ingredient in Eliquis is apixaban, which belongs to a class of medicines known as Factor Xa Inhibitor.

Who makes Eliquis?

Eliquis is manufactured by Bristol-Myers Squibb/Pfizer. It was first approved in 2012.

How can I save money on Eliquis?

You may be able to lower the cost of Eliquis by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Eliquis

Other Cardiovascular medications

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Quick Facts

Manufacturer

Bristol-Myers Squibb/Pfizer

Year Approved

2012

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