Biktarvy vs Cabenuva

A side-by-side look at two hiv medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US BiktarvyUS Cabenuva
Generic namebictegravir/emtricitabine/tenofovir alafenamidecabotegravir/rilpivirine
Drug classIntegrase Inhibitor + NRTI CombinationIntegrase Inhibitor / NNRTI (Long-Acting Injectable)
TreatsHIV-1 infectionHIV-1 infection
CategoryHIVHIV
ManufacturerGilead SciencesViiV Healthcare
Year approved20182021
FDA warningBlack box warningModerate warnings
Est. TV ad spend$180M
Common side effectsWorsening of hepatitis B after stopping, Headache, Diarrhea, NauseaInjection site reactions, Fever, Fatigue, Headache

Frequently asked questions

Is Biktarvy or Cabenuva better?

Neither is universally "better." Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) and Cabenuva (cabotegravir/rilpivirine) are both used for hiv, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Biktarvy and Cabenuva?

Biktarvy is a Integrase Inhibitor + NRTI Combination made by Gilead Sciences, while Cabenuva is a Integrase Inhibitor / NNRTI (Long-Acting Injectable) made by ViiV Healthcare. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Biktarvy has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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