Breo Ellipta vs Fasenra

A side-by-side look at two respiratory medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US Breo ElliptaUS Fasenra
Generic namefluticasone/vilanterolbenralizumab
Drug classICS/LABA InhalerIL-5 Receptor Antagonist (Biologic)
TreatsAsthma, COPDSevere eosinophilic asthma
CategoryRespiratoryRespiratory
ManufacturerGSKAstraZeneca
Year approved20132017
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$100M$80M
Common side effectsOral thrush, Throat irritation, Headache, Common cold symptomsHeadache, Sore throat, Allergic reactions, Injection site reactions

Frequently asked questions

Is Breo Ellipta or Fasenra better?

Neither is universally "better." Breo Ellipta (fluticasone/vilanterol) and Fasenra (benralizumab) are both used for respiratory, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Breo Ellipta and Fasenra?

Breo Ellipta is a ICS/LABA Inhaler made by GSK, while Fasenra is a IL-5 Receptor Antagonist (Biologic) made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Breo Ellipta has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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