Breo Ellipta vs Xolair

A side-by-side look at two respiratory medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US Breo ElliptaUS Xolair
Generic namefluticasone/vilanterolomalizumab
Drug classICS/LABA InhalerAnti-IgE Monoclonal Antibody
TreatsAsthma, COPDAllergic asthma, chronic hives, food allergy
CategoryRespiratoryRespiratory
ManufacturerGSKGenentech/Novartis
Year approved20132003
FDA warningNo boxed warningBlack box warning
Est. TV ad spend$100M$95M
Common side effectsOral thrush, Throat irritation, Headache, Common cold symptomsAnaphylaxis (severe allergic reaction), Injection site reactions, Joint pain, Headache

Frequently asked questions

Is Breo Ellipta or Xolair better?

Neither is universally "better." Breo Ellipta (fluticasone/vilanterol) and Xolair (omalizumab) are both used for respiratory, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Breo Ellipta and Xolair?

Breo Ellipta is a ICS/LABA Inhaler made by GSK, while Xolair is a Anti-IgE Monoclonal Antibody made by Genentech/Novartis. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Breo Ellipta has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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