Contrave vs Saxenda

A side-by-side look at two weight management medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US ContraveUS Saxenda
Generic namenaltrexone/bupropionliraglutide
Drug classOpioid Antagonist / Aminoketone CombinationGLP-1 Receptor Agonist
TreatsChronic weight managementChronic weight management
CategoryWeight ManagementWeight Management
ManufacturerCurrax PharmaceuticalsNovo Nordisk
Year approved20142014
FDA warningBlack box warningBlack box warning
Est. TV ad spend
Common side effectsNausea, Constipation, Headache, Increased blood pressureNausea, Diarrhea, Constipation, Risk of thyroid C-cell tumors (boxed warning)

Frequently asked questions

Is Contrave or Saxenda better?

Neither is universally "better." Contrave (naltrexone/bupropion) and Saxenda (liraglutide) are both used for weight management, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Contrave and Saxenda?

Contrave is a Opioid Antagonist / Aminoketone Combination made by Currax Pharmaceuticals, while Saxenda is a GLP-1 Receptor Agonist made by Novo Nordisk. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Contrave has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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