Cosentyx vs Sotyktu

A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US CosentyxUS Sotyktu
Generic namesecukinumabdeucravacitinib
Drug classIL-17A Inhibitor (Biologic)TYK2 Inhibitor
TreatsPlaque psoriasis, psoriatic arthritis, ankylosing spondylitisPlaque psoriasis
CategoryAutoimmuneAutoimmune
ManufacturerNovartisBristol-Myers Squibb
Year approved20152022
FDA warningModerate warningsModerate warnings
Est. TV ad spend$160M$130M
Common side effectsRespiratory infections, Inflammatory bowel disease, Fungal infections, Injection site reactionsCommon cold symptoms, Increased infections, Cold sores, Mouth sores

Frequently asked questions

Is Cosentyx or Sotyktu better?

Neither is universally "better." Cosentyx (secukinumab) and Sotyktu (deucravacitinib) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Cosentyx and Sotyktu?

Cosentyx is a IL-17A Inhibitor (Biologic) made by Novartis, while Sotyktu is a TYK2 Inhibitor made by Bristol-Myers Squibb. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Cosentyx has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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