Lipitor vs Crestor

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US LipitorUS Crestor
Generic nameatorvastatinrosuvastatin
Drug classStatinStatin
TreatsHigh cholesterol, cardiovascular preventionHigh cholesterol, cardiovascular prevention
CategoryCardiovascularCardiovascular
ManufacturerPfizerAstraZeneca
Year approved19962003
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$60M$45M
Common side effectsMuscle pain or weakness, Liver problems, Increased blood sugar, Memory problemsMuscle pain, Headache, Liver problems, Increased blood sugar

Frequently asked questions

Is Lipitor or Crestor better?

Neither is universally "better." Lipitor (atorvastatin) and Crestor (rosuvastatin) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Lipitor and Crestor?

Lipitor is a Statin made by Pfizer, while Crestor is a Statin made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Lipitor has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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