Mounjaro vs Trulicity

A side-by-side look at two diabetes medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

CA MounjaroCA Trulicity
Generic nametirzepatidedulaglutide
Drug classGIP/GLP-1 Receptor AgonistGLP-1 Receptor Agonist
TreatsType 2 diabetesType 2 diabetes
CategoryDiabetesDiabetes
ManufacturerEli LillyEli Lilly
Year approved20222015
FDA warningBlack box warningBlack box warning
Est. TV ad spend$40M$26M
Common side effectsNausea, Diarrhea, Decreased appetite, VomitingNausea, Diarrhea, Vomiting, Abdominal pain

Frequently asked questions

Is Mounjaro or Trulicity better?

Neither is universally "better." Mounjaro (tirzepatide) and Trulicity (dulaglutide) are both used for diabetes, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Mounjaro and Trulicity?

Mounjaro is a GIP/GLP-1 Receptor Agonist made by Eli Lilly, while Trulicity is a GLP-1 Receptor Agonist made by Eli Lilly. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Mounjaro has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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