Nasonex vs Otrivin

A side-by-side look at two allergy medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

NZ NasonexNZ Otrivin
Generic namemometasonexylometazoline
Drug classCorticosteroidTopical Decongestant
TreatsAllergic rhinitis, hay fever, nasal polypsNasal congestion, cold and sinus relief
CategoryAllergyAllergy
ManufacturerOrganonHaleon
Year approved19971959
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$8M$3M
Common side effectsNosebleeds, Nasal irritation, Headache, Throat irritationRebound congestion with overuse, Nasal dryness, Stinging, Sneezing

Frequently asked questions

Is Nasonex or Otrivin better?

Neither is universally "better." Nasonex (mometasone) and Otrivin (xylometazoline) are both used for allergy, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Nasonex and Otrivin?

Nasonex is a Corticosteroid made by Organon, while Otrivin is a Topical Decongestant made by Haleon. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Nasonex has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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