Nasonex vs Zyrtec

A side-by-side look at two allergy medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

NZ NasonexNZ Zyrtec
Generic namemometasonecetirizine
Drug classCorticosteroidSecond-Generation Antihistamine
TreatsAllergic rhinitis, hay fever, nasal polypsHay fever, allergies, hives
CategoryAllergyAllergy
ManufacturerOrganonJohnson & Johnson
Year approved19971995
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$8M$4M
Common side effectsNosebleeds, Nasal irritation, Headache, Throat irritationDrowsiness, Dry mouth, Fatigue, Headache

Frequently asked questions

Is Nasonex or Zyrtec better?

Neither is universally "better." Nasonex (mometasone) and Zyrtec (cetirizine) are both used for allergy, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Nasonex and Zyrtec?

Nasonex is a Corticosteroid made by Organon, while Zyrtec is a Second-Generation Antihistamine made by Johnson & Johnson. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Nasonex has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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