Ozempic vs Mounjaro

A side-by-side look at two diabetes medications advertised on TV. Informational only — not medical advice.

Share

Information reviewed July 24, 2026

US OzempicUS Mounjaro
Generic namesemaglutidetirzepatide
Drug classGLP-1 Receptor AgonistGIP/GLP-1 Receptor Agonist
TreatsType 2 diabetesType 2 diabetes
CategoryDiabetesDiabetes
ManufacturerNovo NordiskEli Lilly
Year approved20172022
FDA warningModerate warningsBlack box warning
Est. TV ad spend$420M$350M
Common side effectsNausea, Vomiting, Diarrhea, Abdominal painNausea, Diarrhea, Decreased appetite, Vomiting

Frequently asked questions

Is Ozempic or Mounjaro better?

Neither is universally "better." Ozempic (semaglutide) and Mounjaro (tirzepatide) are both used for diabetes, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Ozempic and Mounjaro?

Ozempic is a GLP-1 Receptor Agonist made by Novo Nordisk, while Mounjaro is a GIP/GLP-1 Receptor Agonist made by Eli Lilly. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Ozempic has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

TVPills is independent and not affiliated with, endorsed by, or sponsored by any drug manufacturer or brand. All trademarks are the property of their respective owners. Some links are affiliate links; we may earn a commission at no extra cost to you.