Restasis vs Vabysmo

A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US RestasisUS Vabysmo
Generic namecyclosporine ophthalmic emulsionfaricimab
Drug classCalcineurin Inhibitor (Eye Drop)VEGF/Ang-2 Bispecific Inhibitor (Eye Injection)
TreatsChronic dry eyeWet macular degeneration, diabetic macular edema
CategoryEye HealthEye Health
ManufacturerAbbVie (Allergan)Genentech (Roche)
Year approved20032022
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$100M$85M
Common side effectsBurning sensation, Eye redness, Watery eyes, Blurred visionEye inflammation, Floaters, Increased eye pressure, Blurred vision

Frequently asked questions

Is Restasis or Vabysmo better?

Neither is universally "better." Restasis (cyclosporine ophthalmic emulsion) and Vabysmo (faricimab) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Restasis and Vabysmo?

Restasis is a Calcineurin Inhibitor (Eye Drop) made by AbbVie (Allergan), while Vabysmo is a VEGF/Ang-2 Bispecific Inhibitor (Eye Injection) made by Genentech (Roche). See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Restasis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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