Shingrix vs Arexvy

A side-by-side look at two vaccine medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US ShingrixUS Arexvy
Generic namerecombinant zoster vaccinerespiratory syncytial virus vaccine
Drug classRecombinant Adjuvanted VaccineRecombinant Adjuvanted Vaccine
TreatsShingles preventionRSV prevention in older adults
CategoryVaccineVaccine
ManufacturerGSKGSK
Year approved20172023
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$150M$110M
Common side effectsSore arm, Muscle pain, Fatigue, HeadacheInjection site pain, Fatigue, Muscle pain, Headache

Frequently asked questions

Is Shingrix or Arexvy better?

Neither is universally "better." Shingrix (recombinant zoster vaccine) and Arexvy (respiratory syncytial virus vaccine) are both used for vaccine, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Shingrix and Arexvy?

Shingrix is a Recombinant Adjuvanted Vaccine made by GSK, while Arexvy is a Recombinant Adjuvanted Vaccine made by GSK. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Shingrix has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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