Shingrix vs Gardasil 9

A side-by-side look at two vaccine medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US ShingrixUS Gardasil 9
Generic namerecombinant zoster vaccinehuman papillomavirus 9-valent vaccine
Drug classRecombinant Adjuvanted VaccineVaccine
TreatsShingles preventionHPV-related cancer prevention
CategoryVaccineVaccine
ManufacturerGSKMerck
Year approved20172014
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$150M
Common side effectsSore arm, Muscle pain, Fatigue, HeadacheInjection-site pain, Swelling, Headache, Fever

Frequently asked questions

Is Shingrix or Gardasil 9 better?

Neither is universally "better." Shingrix (recombinant zoster vaccine) and Gardasil 9 (human papillomavirus 9-valent vaccine) are both used for vaccine, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Shingrix and Gardasil 9?

Shingrix is a Recombinant Adjuvanted Vaccine made by GSK, while Gardasil 9 is a Vaccine made by Merck. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Shingrix has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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