Taltz vs Cosentyx

A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US TaltzUS Cosentyx
Generic nameixekizumabsecukinumab
Drug classIL-17A Inhibitor (Biologic)IL-17A Inhibitor (Biologic)
TreatsPlaque psoriasis, psoriatic arthritis, ankylosing spondylitisPlaque psoriasis, psoriatic arthritis, ankylosing spondylitis
CategoryAutoimmuneAutoimmune
ManufacturerEli LillyNovartis
Year approved20162015
FDA warningModerate warningsModerate warnings
Est. TV ad spend$190M$160M
Common side effectsInjection site reactions, Respiratory infections, Inflammatory bowel disease, Low white blood cell countRespiratory infections, Inflammatory bowel disease, Fungal infections, Injection site reactions

Frequently asked questions

Is Taltz or Cosentyx better?

Neither is universally "better." Taltz (ixekizumab) and Cosentyx (secukinumab) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Taltz and Cosentyx?

Taltz is a IL-17A Inhibitor (Biologic) made by Eli Lilly, while Cosentyx is a IL-17A Inhibitor (Biologic) made by Novartis. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Taltz has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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