Trelegy Ellipta vs Advair Diskus

A side-by-side look at two respiratory medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US Trelegy ElliptaUS Advair Diskus
Generic namefluticasone/umeclidinium/vilanterolfluticasone/salmeterol
Drug classInhaled Corticosteroid + LAMA + LABAInhaled Corticosteroid / LABA Combination
TreatsCOPD, asthmaAsthma and COPD
CategoryRespiratoryRespiratory
ManufacturerGSKGSK
Year approved20172000
FDA warningNo boxed warningModerate warnings
Est. TV ad spend$200M
Common side effectsThrush, Respiratory infections, Headache, CoughThrush (mouth infection), Hoarse voice, Headache, Throat irritation

Frequently asked questions

Is Trelegy Ellipta or Advair Diskus better?

Neither is universally "better." Trelegy Ellipta (fluticasone/umeclidinium/vilanterol) and Advair Diskus (fluticasone/salmeterol) are both used for respiratory, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Trelegy Ellipta and Advair Diskus?

Trelegy Ellipta is a Inhaled Corticosteroid + LAMA + LABA made by GSK, while Advair Diskus is a Inhaled Corticosteroid / LABA Combination made by GSK. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Trelegy Ellipta has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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