Trelegy Ellipta vs Daliresp

A side-by-side look at two respiratory medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US Trelegy ElliptaUS Daliresp
Generic namefluticasone/umeclidinium/vilanterolroflumilast
Drug classInhaled Corticosteroid + LAMA + LABAPDE4 Inhibitor (Oral)
TreatsCOPD, asthmaChronic obstructive pulmonary disease (COPD)
CategoryRespiratoryRespiratory
ManufacturerGSKAstraZeneca
Year approved20172011
FDA warningNo boxed warningModerate warnings
Est. TV ad spend$200M
Common side effectsThrush, Respiratory infections, Headache, CoughDiarrhea, Weight loss, Nausea, Headache

Frequently asked questions

Is Trelegy Ellipta or Daliresp better?

Neither is universally "better." Trelegy Ellipta (fluticasone/umeclidinium/vilanterol) and Daliresp (roflumilast) are both used for respiratory, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Trelegy Ellipta and Daliresp?

Trelegy Ellipta is a Inhaled Corticosteroid + LAMA + LABA made by GSK, while Daliresp is a PDE4 Inhibitor (Oral) made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Trelegy Ellipta has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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