Tyrvaya vs Miebo

A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US TyrvayaUS Miebo
Generic namevarenicline nasal sprayperfluorohexyloctane
Drug classNicotinic Acetylcholine Receptor Agonist (Nasal)Semifluorinated Alkane (Eye Drop)
TreatsDry eye diseaseDry eye disease
CategoryEye HealthEye Health
ManufacturerViatrisBausch + Lomb
Year approved20212023
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend
Common side effectsSneezing, Cough, Throat irritation, Nose irritationBlurred vision, Eye redness, Temporary discomfort on application

Frequently asked questions

Is Tyrvaya or Miebo better?

Neither is universally "better." Tyrvaya (varenicline nasal spray) and Miebo (perfluorohexyloctane) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Tyrvaya and Miebo?

Tyrvaya is a Nicotinic Acetylcholine Receptor Agonist (Nasal) made by Viatris, while Miebo is a Semifluorinated Alkane (Eye Drop) made by Bausch + Lomb. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Tyrvaya has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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