Ubrelvy vs Ajovy

A side-by-side look at two neurology medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US UbrelvyUS Ajovy
Generic nameubrogepantfremanezumab
Drug classCGRP Receptor AntagonistCGRP Antagonist (Biologic)
TreatsAcute migraineMigraine prevention
CategoryNeurologyNeurology
ManufacturerAbbVieTeva
Year approved20192018
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$160M$70M
Common side effectsNausea, Drowsiness, Dry mouthInjection site reactions, Allergic reactions

Frequently asked questions

Is Ubrelvy or Ajovy better?

Neither is universally "better." Ubrelvy (ubrogepant) and Ajovy (fremanezumab) are both used for neurology, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Ubrelvy and Ajovy?

Ubrelvy is a CGRP Receptor Antagonist made by AbbVie, while Ajovy is a CGRP Antagonist (Biologic) made by Teva. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Ubrelvy has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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