Vascepa vs Crestor

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US VascepaUS Crestor
Generic nameicosapent ethylrosuvastatin
Drug classOmega-3 Fatty Acid (EPA)Statin
TreatsHigh triglycerides, cardiovascular risk reductionHigh cholesterol, cardiovascular prevention
CategoryCardiovascularCardiovascular
ManufacturerAmarinAstraZeneca
Year approved20122003
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$90M$45M
Common side effectsAtrial fibrillation, Bleeding risk, Joint pain, SwellingMuscle pain, Headache, Liver problems, Increased blood sugar

Frequently asked questions

Is Vascepa or Crestor better?

Neither is universally "better." Vascepa (icosapent ethyl) and Crestor (rosuvastatin) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Vascepa and Crestor?

Vascepa is a Omega-3 Fatty Acid (EPA) made by Amarin, while Crestor is a Statin made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Vascepa has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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