Wegovy vs Mounjaro

A side-by-side look at Wegovy and Mounjaro, two prescription medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US WegovyUS Mounjaro
Generic namesemaglutidetirzepatide
Drug classGLP-1 Receptor AgonistGIP/GLP-1 Receptor Agonist
TreatsChronic weight management, cardiovascular risk reductionType 2 diabetes
CategoryWeight ManagementDiabetes
ManufacturerNovo NordiskEli Lilly
Year approved20212022
FDA warningBlack box warningBlack box warning
Est. TV ad spend$380M$350M
Common side effectsNausea, Diarrhea, Vomiting, ConstipationNausea, Diarrhea, Decreased appetite, Vomiting

Frequently asked questions

Is Wegovy or Mounjaro better?

Neither is universally "better." Wegovy (semaglutide) is used for chronic weight management, cardiovascular risk reduction, while Mounjaro (tirzepatide) is used for type 2 diabetes, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Wegovy and Mounjaro?

Wegovy is a GLP-1 Receptor Agonist made by Novo Nordisk, while Mounjaro is a GIP/GLP-1 Receptor Agonist made by Eli Lilly. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Wegovy has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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