Xarelto vs Lipitor

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

CA XareltoCA Lipitor
Generic namerivaroxabanatorvastatin
Drug classFactor Xa InhibitorStatin
TreatsBlood clots, atrial fibrillationHigh cholesterol, cardiovascular prevention
CategoryCardiovascularCardiovascular
ManufacturerBayer/JanssenPfizer
Year approved20121997
FDA warningBlack box warningNo boxed warning
Est. TV ad spend$28M$8M
Common side effectsSerious bleeding risk, Bruising, Prolonged bleeding, DizzinessMuscle pain, Liver problems, Increased blood sugar, Digestive issues

Frequently asked questions

Is Xarelto or Lipitor better?

Neither is universally "better." Xarelto (rivaroxaban) and Lipitor (atorvastatin) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Xarelto and Lipitor?

Xarelto is a Factor Xa Inhibitor made by Bayer/Janssen, while Lipitor is a Statin made by Pfizer. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Xarelto has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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