Xolair vs Fasenra

A side-by-side look at two respiratory medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US XolairUS Fasenra
Generic nameomalizumabbenralizumab
Drug classAnti-IgE Monoclonal AntibodyIL-5 Receptor Antagonist (Biologic)
TreatsAllergic asthma, chronic hives, food allergySevere eosinophilic asthma
CategoryRespiratoryRespiratory
ManufacturerGenentech/NovartisAstraZeneca
Year approved20032017
FDA warningBlack box warningNo boxed warning
Est. TV ad spend$95M$80M
Common side effectsAnaphylaxis (severe allergic reaction), Injection site reactions, Joint pain, HeadacheHeadache, Sore throat, Allergic reactions, Injection site reactions

Frequently asked questions

Is Xolair or Fasenra better?

Neither is universally "better." Xolair (omalizumab) and Fasenra (benralizumab) are both used for respiratory, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Xolair and Fasenra?

Xolair is a Anti-IgE Monoclonal Antibody made by Genentech/Novartis, while Fasenra is a IL-5 Receptor Antagonist (Biologic) made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Xolair has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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