Xtandi vs Lynparza
A side-by-side look at two oncology medications advertised on TV. Informational only — not medical advice.
| US Xtandi | US Lynparza | |
|---|---|---|
| Generic name | enzalutamide | olaparib |
| Drug class | Androgen Receptor Inhibitor | PARP Inhibitor |
| Treats | Prostate cancer | Ovarian, breast, prostate, and pancreatic cancers |
| Category | Oncology | Oncology |
| Manufacturer | Astellas/Pfizer | AstraZeneca |
| Year approved | 2012 | 2014 |
| FDA warning | Moderate warnings | Moderate warnings |
| Est. TV ad spend | $90M | — |
| Common side effects | Fatigue, Hot flashes, High blood pressure, Falls | Nausea, Fatigue, Low blood counts, Risk of blood cancers (MDS/AML) |
Frequently asked questions
Is Xtandi or Lynparza better?
Neither is universally "better." Xtandi (enzalutamide) and Lynparza (olaparib) are both used for oncology, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.
What's the difference between Xtandi and Lynparza?
Xtandi is a Androgen Receptor Inhibitor made by Astellas/Pfizer, while Lynparza is a PARP Inhibitor made by AstraZeneca. See the table above for a side-by-side breakdown.
Which one spends more on TV ads?
Xtandi has the larger estimated TV advertising budget of the two.