Caplyta vs Adderall

A side-by-side look at two mental health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US CaplytaUS Adderall
Generic namelumateperoneamphetamine/dextroamphetamine
Drug classAtypical AntipsychoticCNS Stimulant
TreatsSchizophrenia, bipolar depressionADHD, narcolepsy
CategoryMental HealthMental Health
ManufacturerIntra-Cellular TherapiesTeva
Year approved20191996
FDA warningBlack box warningBlack box warning
Est. TV ad spend$130M$1M
Common side effectsDrowsiness, Dry mouth, Dizziness, NauseaHigh potential for abuse and dependence, Insomnia, Decreased appetite, Increased heart rate

Frequently asked questions

Is Caplyta or Adderall better?

Neither is universally "better." Caplyta (lumateperone) and Adderall (amphetamine/dextroamphetamine) are both used for mental health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Caplyta and Adderall?

Caplyta is a Atypical Antipsychotic made by Intra-Cellular Therapies, while Adderall is a CNS Stimulant made by Teva. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Caplyta has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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