Cosentyx vs Tremfya

A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.

Share

Information reviewed July 24, 2026

US CosentyxUS Tremfya
Generic namesecukinumabguselkumab
Drug classIL-17A Inhibitor (Biologic)IL-23 Inhibitor (Biologic)
TreatsPlaque psoriasis, psoriatic arthritis, ankylosing spondylitisPlaque psoriasis, psoriatic arthritis
CategoryAutoimmuneAutoimmune
ManufacturerNovartisJanssen
Year approved20152017
FDA warningModerate warningsModerate warnings
Est. TV ad spend$160M$140M
Common side effectsRespiratory infections, Inflammatory bowel disease, Fungal infections, Injection site reactionsRespiratory infections, Headache, Injection site reactions, Joint pain

Frequently asked questions

Is Cosentyx or Tremfya better?

Neither is universally "better." Cosentyx (secukinumab) and Tremfya (guselkumab) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Cosentyx and Tremfya?

Cosentyx is a IL-17A Inhibitor (Biologic) made by Novartis, while Tremfya is a IL-23 Inhibitor (Biologic) made by Janssen. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Cosentyx has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

TVPills is independent and not affiliated with, endorsed by, or sponsored by any drug manufacturer or brand. All trademarks are the property of their respective owners. Some links are affiliate links; we may earn a commission at no extra cost to you.