Eliquis vs Brilinta

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US EliquisUS Brilinta
Generic nameapixabanticagrelor
Drug classFactor Xa InhibitorP2Y12 Platelet Inhibitor (Antiplatelet)
TreatsBlood clots, atrial fibrillationAcute coronary syndrome, heart attack prevention
CategoryCardiovascularCardiovascular
ManufacturerBristol-Myers Squibb/PfizerAstraZeneca
Year approved20122011
FDA warningBlack box warningBlack box warning
Est. TV ad spend$350M$120M
Common side effectsSerious bleeding risk, Bruising easily, Prolonged bleeding from cuts, Blood in urine or stoolBleeding, Shortness of breath, Bruising, Headache

Frequently asked questions

Is Eliquis or Brilinta better?

Neither is universally "better." Eliquis (apixaban) and Brilinta (ticagrelor) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Eliquis and Brilinta?

Eliquis is a Factor Xa Inhibitor made by Bristol-Myers Squibb/Pfizer, while Brilinta is a P2Y12 Platelet Inhibitor (Antiplatelet) made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Eliquis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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