Eliquis vs Lisinopril

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US EliquisUS Lisinopril
Generic nameapixabanlisinopril
Drug classFactor Xa InhibitorACE Inhibitor
TreatsBlood clots, atrial fibrillationHigh blood pressure, heart failure
CategoryCardiovascularCardiovascular
ManufacturerBristol-Myers Squibb/PfizerVarious (generic)
Year approved20121987
FDA warningBlack box warningBlack box warning
Est. TV ad spend$350M$1M
Common side effectsSerious bleeding risk, Bruising easily, Prolonged bleeding from cuts, Blood in urine or stoolDry cough, Dizziness, High potassium, Headache

Frequently asked questions

Is Eliquis or Lisinopril better?

Neither is universally "better." Eliquis (apixaban) and Lisinopril (lisinopril) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Eliquis and Lisinopril?

Eliquis is a Factor Xa Inhibitor made by Bristol-Myers Squibb/Pfizer, while Lisinopril is a ACE Inhibitor made by Various (generic). See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Eliquis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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