Eylea vs Tyrvaya
A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.
| US Eylea | US Tyrvaya | |
|---|---|---|
| Generic name | aflibercept | varenicline nasal spray |
| Drug class | VEGF Inhibitor (Eye Injection) | Nicotinic Acetylcholine Receptor Agonist (Nasal) |
| Treats | Wet macular degeneration, diabetic eye disease | Dry eye disease |
| Category | Eye Health | Eye Health |
| Manufacturer | Regeneron | Viatris |
| Year approved | 2011 | 2021 |
| FDA warning | No boxed warning | No boxed warning |
| Est. TV ad spend | $90M | — |
| Common side effects | Eye floaters, Eye pain, Increased eye pressure, Bleeding in the eye | Sneezing, Cough, Throat irritation, Nose irritation |
Frequently asked questions
Is Eylea or Tyrvaya better?
Neither is universally "better." Eylea (aflibercept) and Tyrvaya (varenicline nasal spray) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.
What's the difference between Eylea and Tyrvaya?
Eylea is a VEGF Inhibitor (Eye Injection) made by Regeneron, while Tyrvaya is a Nicotinic Acetylcholine Receptor Agonist (Nasal) made by Viatris. See the table above for a side-by-side breakdown.
Which one spends more on TV ads?
Eylea has the larger estimated TV advertising budget of the two.