Humira vs Skyrizi
A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.
| CA Humira | CA Skyrizi | |
|---|---|---|
| Generic name | adalimumab | risankizumab |
| Drug class | TNF Inhibitor (Biologic) | IL-23 Inhibitor (Biologic) |
| Treats | Rheumatoid arthritis, psoriasis, Crohn's disease | Plaque psoriasis, psoriatic arthritis, Crohn's disease |
| Category | Autoimmune | Autoimmune |
| Manufacturer | AbbVie | AbbVie |
| Year approved | 2002 | 2019 |
| FDA warning | Black box warning | Moderate warnings |
| Est. TV ad spend | $95M | $48M |
| Common side effects | Serious infections, Increased cancer risk, Allergic reactions, Injection site reactions | Respiratory infections, Headache, Fatigue, Injection site reactions |
Frequently asked questions
Is Humira or Skyrizi better?
Neither is universally "better." Humira (adalimumab) and Skyrizi (risankizumab) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.
What's the difference between Humira and Skyrizi?
Humira is a TNF Inhibitor (Biologic) made by AbbVie, while Skyrizi is a IL-23 Inhibitor (Biologic) made by AbbVie. See the table above for a side-by-side breakdown.
Which one spends more on TV ads?
Humira has the larger estimated TV advertising budget of the two.